Director of Science

About MyHeritage

MyHeritage is a global leader in family history and consumer DNA testing, enriching the lives of millions worldwide by enabling them to uncover more about themselves and where they belong. With a suite of intuitive products, billions of historical records, an affordable at-home DNA test, and AI-powered photo tools, MyHeritage creates a meaningful discovery experience that is deeply rewarding.

About the Position

We are looking for a Director of Science to guide MyHeritage’s scientific research and development in genetics and genomics. As the company expands beyond genetic genealogy into health-related products, including clinical genomics, high coverage whole genome sequencing, and wellness and trait analyses, this role will be central to building the algorithms, pipelines, and scientific standards behind them. It will also support the continued development of our core genetic genealogy products, including ethnicity estimation, relationship inference, local ancestry, and more.

The ideal candidate combines deep expertise in computational genomics, method development, and machine learning with hands-on clinical genomics experience, strong leadership, and a proven ability to execute in a dynamic, consumer-facing environment.

Your work will directly impact millions of users worldwide, helping them discover their health, ancestry, and connect with family through science. You’ll apply cutting-edge methods to analyze millions of DNA samples and family trees, leveraging one of the largest consumer genetics datasets in the world.

Responsibilities

• Scientific leadership: Define and execute the scientific roadmap aligned with company goals, including the expansion into health and clinical genomics.
• Team leadership: Manage and mentor a team of senior scientists and data scientists. Provide technical direction, support professional growth, and foster a culture of scientific excellence.
• Algorithmic research: Lead the design, development, and validation of scalable, production-ready algorithms and pipelines. These include sequencing analysis and variant interpretation, carrier screening, polygenic risk scores, and new genetic genealogy methods.
• Collaboration and communication: Work closely with engineering, product, and data teams to translate research into user-facing features. Clearly communicate scientific concepts, limitations, and progress internally and externally.

Requirements

• Ph.D. in Computational Biology, Bioinformatics, Genetics, Computer Science, or a related quantitative field.
• Strong track record in computational genomics and algorithm development.
• Hands-on experience with clinical genomics and analysis of sequencing data (WGS/WES), including variant calling, annotation, and interpretation.
• Experience applying machine learning or statistical modeling to biological data.
• 5+ years of experience in scientific research, including 3+ years in a leadership role.
• Experience with large-scale genomic datasets and production-scale computational pipelines.
• Excellent written and verbal communication skills, and a demonstrated ability to lead projects and collaborate across disciplines.

Nice to Have

• Experience in regulated or clinical genomics settings, polygenic risk scores, or carrier screening.
• Familiarity with population or statistical genetics.
• AWS experience.

We Offer

• Join a purpose-driven company helping people discover their heritage through the power of science.
• Be part of a collaborative, international team driven by innovation and scientific discovery.
• Enjoy a hybrid work environment with flexibility and autonomy.
• Hybrid work model
• Modern, beautiful offices in Or Yehuda and Tel Aviv with shuttle service from Tel Aviv and employee parking (for our Or Yehuda employees)
• On-site Gym and Pilates classes
• Dog-friendly office
• Well-stocked kitchens and a monthly meal allowance
• Fully funded supplemental health insurance

About the Company

MyHeritage is a global leader in family history and consumer DNA testing, enriching the lives of millions worldwide by enabling them to uncover more about themselves and where they belong. With a suite of intuitive products, billions of historical records, an affordable at-home DNA test, and AI-powered photo tools, MyHeritage creates a meaningful discovery experience that is deeply rewarding.