PhD Chemist

About the Position

We are seeking a PhD Chemist with expertise in synthetic organic chemistry to join our R&D team in Swords, Co. Dublin, Republic of Ireland. SK pharmteco is a global Contract Development and Manufacturing organisation (CDMO) with state-of-the-art facilities in Korea, US, France, and Ireland. Our mission is to 'produce and deliver life-changing therapies that improve patient outcomes and save lives'. The SK pharmteco Small Molecule, Europe, facility located in Swords, Co Dublin, Ireland has led the way in the development, scale-up, and commercial manufacture of Active Pharmaceutical Ingredients (APIs) and Chemical Intermediates for over 60 years.

Responsibilities

• Lead development projects in the laboratory, including route scouting and route development, proof of concept, crystallization optimization, and process safety assessment.
• Provide technical support to the manufacture of APIs and intermediates manufactured at SK biotek Ireland, with a focus on optimization and investigation support.
• Identify and implement projects to optimize processes, considering scale-up and manufacturing aspects and Critical to Quality Attributes.
• Leverage data monitoring and PAT tools in the laboratory such as FBRM, Raman, IR, as required.
• Identify and implement new technologies to support development for the business needs of the site.
• Coordinate tech transfer activities for introduction of new clinical and commercial products to the site, including process development in the laboratory, customer engagement, troubleshooting, documentation, and campaign readiness.
• Support chemistry assessments for new products as required.
• Lead optimization projects on throughput and yield in collaboration with Operations engineers.
• Support continuous process verification through collection and trending of data for commercial products, identifying Out of Trends (OOT) and Statistical Alert Events (SAE) and leading investigations where required with support from R&D engineers and analytical chemists.
• Actively participate in manufacturing campaign performance support teams.
• Lead and support quality and safety investigations.
• Collaborate with R&D analytical chemists and Operations engineers on new products introduction and scale-up activities.

Requirements

• PhD in organic chemistry
• Strong technical background in chemistry
• 1+ years of experience in the pharmaceutical industry
• Strong interpersonal and communication skills and demonstrated ability to work across a matrix.
• Excellent problem-solving skills and commitment to continuous improvement.
• Experience in project management, troubleshooting, and continuous process verification.
• Demonstrated capability in the use of standard tools for root cause analysis and standard statistical tools.
• Demonstrated capability in the use of various analytical/diagnostic tools including PAT, chromatography, and process safety.
• Ensure that GMP, Quality, Health & Safety are considered in all aspects of the role.

We Offer

• Competitive base salary of 50,000 EUR per year
• Annual bonus linked to business results
• Excellent opportunities for career enhancement and personal development
• A well-established further education program
• Pension scheme
• Private healthcare

About the Company

SK pharmteco is a global Contract Development and Manufacturing organisation (CDMO) with state-of-the-art facilities in Korea, US, France, and Ireland. We are part of SK Inc., a Korean company with revenues of $99 billion in 2023. Our mission is to ‘produce and deliver life-changing therapies that improve patient outcomes and save lives’. The SK pharmteco Small Molecule, Europe, facility located in Swords, Co Dublin, Ireland has led the way in the development, scale-up, and commercial manufacture of Active Pharmaceutical Ingredients (APIs) and Chemical Intermediates for over 60 years. With a talented workforce, exceptional technical capabilities, and facilities, we have made some of the world’s most important medicines and continue to do so. Further information on SK pharmteco can be found at www.skpharmteco.com.